FURTHER RESEARCH ON DETERMINATION OF DNA IN BLOOD AS AN INDEX OF RHEUMATIC PROCESS ACTIVITY
Abstract
In rheumatic fever patients with an acute, subacute, chronic, and latent course of the disease (activities III, II and I) the DNA content of the leukocytes is increased in most cases, even when reduced to one milliliter of blood. Parallel with the increase of the DNA content, however, in patients suffering from the continuously relapsing form of the disease there is more often an absolute drop in the amount of DNA in the blood, and this drop hardly changes in the course of subsequent examinations. In most patients suffering from an acute or subacute form of the disease (activities III and II) the DNA content returns to normal as the activity of the process diminishes. In patients suffering from a chronic course of the disease (activity I), in most cases this index does not return to normal before the patients' release from the ward. A higher DNA content in the blood is found in most patients suffering from progressive polyarthritis, especially in the acute course of the process.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 17, 1968
- Accession Number
- AD0675381
Entities
People
- A. B. Zborovskiy
- V. A. Shkolnikova-bespalova
Organizations
- United States Army Biological Warfare Laboratories