MULTIPLE COMPARISONS OF SURVIVAL TIMES.
Abstract
Let P sub t be the probability of a patient surviving from a suitably selected time O to time t under a particular treatment and P asterisk sub t under an alternative treatment. In a previous paper we have studied the problem of simultaneously estimating the difference P sub t - P asterisk sub t for t = 1,2,...,T from observations collected in clinical follow-up where some patients may be lost to observations before T. Assuming a Markov chain model, we have obtained confidence intervals such that as the number of patients is indifinitely increased, their joint confidence coefficient has a prescribed lower bound in the limit. In this paper we show how these intervals can be shortened, by generalizing a result of Goodman about contrasts of transition probabilities of a Markov chain. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Aug 28, 1968
- Accession Number
- AD0675595
Entities
People
- Agnes Berger
- Ruth Z. Gold
Organizations
- Columbia University