A CYTOCHEMICAL STUDY OF THE NEURONAL GOLGI APPARATUS IN EXPERIMENTAL DIPHTHERITIC ENCEPHALITIS IN RATS

Abstract

The distribution of nucleoside diphosphatase activity in the rat brain is described and its ability to visualize the neuronal Golgi apparatus is illustrated. Fragmentation and dissolution of the Golgi apparatus, as seen in the cytochemical preparations, is described in neurons injured by diphtheria toxin. Marked changes in the lysosomes occur before those in the Golgi apparatus. The usefulness in neurology and neuropathology of the cytochemical staining procedures for the Golgi apparatus is briefly discussed.

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Document Details

Document Type
Technical Report
Publication Date
Jan 05, 1962
Accession Number
AD0675629

Entities

People

  • Alex B. Novikoff
  • Norwin H. Becker
  • Sidney Goldfischer

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Brain
  • Brain Stem
  • Cell Membrane
  • Cells
  • Central Nervous System
  • Golgi Apparatus
  • Medical Personnel
  • Membranes
  • Microvessels
  • Navy
  • Nervous System
  • Neuroglia
  • Neurons
  • Neurosciences
  • Organelles
  • Rodents

Fields of Study

  • Biology

Readers

  • Molecular and Cellular Biochemistry
  • Neuroscience