MULTIPLE PROPERTIES OF CL. BOTULINUM TOXIN,

Abstract

Testing Cl. botulinum toxin type A at various times after its preparation it was found that the toxin was not always toxic to the same degree for albino mice and guinea pigs. With the aging of toxin, the toxin's titer decreased to a greater extent for mice and to a lesser degree for guinea pigs. Such qualitative change in properties of Cl. botulinum toxin was noticed only with a decrease in titer as a result of natural aging; it was absent after artificial decrease of titer, e.g. with a partial inactivation of the titer following thermal processing. (Author)

Document Details

Document Type
Technical Report
Publication Date
Feb 01, 1966
Accession Number
AD0675844

Entities

People

  • I. N. Morgunov
  • S. M. Minervin

Organizations

  • United States Army Biological Warfare Laboratories

Tags

DTIC Thesaurus Topics

  • Anatomy
  • Animals
  • Biological Sciences
  • Cells (Biology)
  • Eukaryotes
  • Mammals
  • Neuromuscular Agents
  • Rodents

Fields of Study

  • Biology

Readers

  • Mathematics or Statistics
  • Microbial Pathology
  • Toxicology/Environmental Toxicology