ON THE PHYSIOLOGICAL MECHANISMS OF THE POTENTIATION EFFECT OF TYPES A AND B BOTULINAL TOXINS IN THE ORGANISM
Abstract
An attempt was made to reveal the role of mediator component in potentiation of the botulism action. The author demonstrated that artificial stimulation of adrenergic processes in the poisoned body by pharmacological or bacterial means results in considerable potentiation of the pathogenic effect of this toxin. On the contrary, depression of these processes by a ganglioblocking preparation (tetamon-I), or activation of cholinreactive systems by cholinchloride and acetylcholinechloride decreases the pathogenic effect of botulism.
Document Details
- Document Type
- Technical Report
- Publication Date
- Feb 01, 1966
- Accession Number
- AD0675846
Entities
People
- V. V. Mikhailov
Organizations
- United States Army Biological Warfare Laboratories