BOTULISM CAUSED BY INHALATION

Abstract

This report discusses three cases of laboratory intoxication caused by the inhalation of dust that contained botulinal toxin describing the possibilities of resorption by way of the pharyngonasal cavity and by the respiratory tract. A rare occurrence of the toxic infection involving botulism is also described. The botulinal poisoning has an inhibitive effect on acetylcholine synthesis, or on acetylcholine secretion of the cholinergic nerve fibers and leads to disturbances of the neuromuscular transference at the end plates. Hence, a treatment with acetylcholine seems to have a particular justification in addition to the doses of antiserum, and general therapeutics. The necessity of having other antisera available besides a horse serum is explained.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Feb 01, 1966
Accession Number
AD0675855

Entities

People

  • E. Holzer

Organizations

  • United States Army Biological Warfare Laboratories

Tags

DTIC Thesaurus Topics

  • Animals
  • Blood
  • Blood Transfusions
  • Death
  • Digestive System Processes
  • Diseases And Disorders
  • Health Services
  • Immune Serums
  • Infection
  • Medical Personnel
  • Nervous System
  • Poisoning
  • Rodents
  • Therapy

Fields of Study

  • Medicine

Readers

  • Cardiovascular Physiology
  • Neurotoxicology
  • Systems Analysis and Design