DISTURBANCE IN THE CENTRAL RESPIRATORY CONTROL DURING BOTULINAL INTOXICATION

Abstract

To study functional disturbances of central portions of the nervous regulation of respiration in botulin intoxication, the rhythmic and coordination activity of medullary respiratory centre was investigated in rabbits and cats. The paralyzing effect of botulin on respiration was analyzed by stimulating the ventramedial area of the brain stem by means of electric current and by eliminating the action potentials from the central and of the phrenic nerve. This toxin inhibited the coordination activity of respiratory centre and produced no significant effect on the rhythmic activity.

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Document Details

Document Type
Technical Report
Publication Date
Feb 01, 1966
Accession Number
AD0675857

Entities

People

  • V. N. Abrosimov

Organizations

  • United States Army Biological Warfare Laboratories

Tags

DTIC Thesaurus Topics

  • Amplitude
  • Artificial Respiration
  • Bacterial Toxins
  • Botulism
  • Brain
  • Brain Stem
  • Diseases And Disorders
  • Electric Current
  • Electrodes
  • Frequency
  • Intoxication
  • Nerves
  • Peripheral Nervous System
  • Respiration
  • Respiration Disorders
  • Skeletal Muscle

Fields of Study

  • Medicine

Readers

  • Microbial Pathology
  • Neuroscience