PATHOMORPHOLOGICAL CHANGES IN RABBIT ORGANS ACTUATED BY BOTULISM MICROBES AND TYPE A AND E BOTULINAL TOXINS
Abstract
Experiments were conducted on 20 rabbits given pure toxin and infected with microbes + botulism toxins of A and E type. Pathomorphological studies showed that the actions of these pathogenic factors are different for the one and the other types of botulism pathogenes. Characteristic of the A type botulism are hemodynamic disorders of the endothelium with formation of perimural venous thrombi, metabolic disorders with the prevalence of hydropic dystrophy. The action of the E type botulism pathogene causes deep changes in the parenchyma including necrosis and also caused a peculiar swelling in the connective tissue. The cellular reaction was slightly expressed in both types of pathogenes.
Document Details
- Document Type
- Technical Report
- Publication Date
- Feb 01, 1966
- Accession Number
- AD0675876
Entities
People
- E. A. Uspenskii
Organizations
- United States Army Biological Warfare Laboratories