GLUCOSE TOLERANCE IN DOGS EXPOSED TO ALTITUDE AND DRUG ADMINISTRATION: MEPERIDINE.
Abstract
The rate of disappearance of an injected glucose load from the blood of dogs exposed to a simulated altitude of 27,000 ft. was compared to similar glucose tolerance at ground level. All dogs were anesthetized and maintained on the same PO2 in the inspired air (152 mm. Hg PO2). In addition, 2.0 mg./kg. Demerol (meperidine) were administered intravenously to the dogs under both atmospheric conditions. A significant increase was seen in the K-value of the nondrug dogs exposed to simulated altitude (P < .05). There was no significant difference between drug and nondrug dogs at altitude or between drug and nondrug dogs at ground level. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 01, 1968
- Accession Number
- AD0676147
Entities
People
- Albert T. Bernardini
- Martin Taub
Organizations
- United States Air Force School of Aerospace Medicine