DRY LIVING TULAREMIA VACCINE OF NIIEG OF THE RED ARMY. REPORT 2 (TULIAREMIINAYA SUKHAYA ZHIVAYA VAKTSINA NIIEG KRASNOI ARMII. SOOBSCHENIE 2)

Abstract

The dry living tularemia vaccine of NIIEG, prepared from vaccinal strains, is capable of preserving its activity for a long time (up to 1.5-2 years). Of the two strains proposed by Gaiskii - Ondatra IV and No. 15 - the most suitable for vaccination of men is the strain No. 15. The dry living tularemia vaccine from the strain No. 15 Possesses high immunogenic properties both for laboratory animals (guinea pigs and white mice) and for men. The safety of the dry living tularemia vaccine has been demonstrated on experimental animals and on a large number of men (over 30,000 men have been inoculated). For vaccination of men it is recommended that the dry living tularemia vaccine be employed once in doses ranging from 10 to 25 million microbes. The new strain No. 10 which we found was high immunogenic properties and can apparently be, after a preliminary testing on men, employed for preparation of a polyvaient dry living tularemia vaccine.

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 1968
Accession Number
AD0676336

Entities

People

  • M. M. Faibich
  • T. S. Tamarina

Organizations

  • United States Army Biological Warfare Laboratories

Tags

DTIC Thesaurus Topics

  • Animals
  • High Vacuum
  • Immunity
  • Infection
  • Laboratory Animals
  • Lethal Dosage
  • Microorganisms
  • Rodents
  • Scientific Research
  • Tickborne Diseases
  • Vaccination
  • Vaccines
  • Wound Infections

Readers

  • Immunology

Technology Areas

  • Biotechnology