THE INFLUENCE OF TISSUE THERAPY ON THE BUBO OF RABBITS DURING TULAREMIA
Abstract
In rabbits with experimental tularemia with the presence of a durative unresolving bubo with the help of tissue therapy, it is possible to obtain a full or partial resolvation of the bubo. Application of splenitis tissues proved effective on a neck bubo of 2 years 7 months duration fully resolved 10 months after a two fold implantation. In two rabbits, inguinal bubos, present for two years three months and two years seven months, receded by one-third, while in rabbits not subjected to implantation, remained without any noticeable change. A one day rise in temperature, and also observed leukocytosis from the second week after the 1st and 2nd implantations, can be explained by the introduction of the biogenic stimulatives, because analogical appearances were observed also in the controlled well rabbits, also having received implantations. For definitive conclusions of the importance of the application of tissue therapy for durative unresolving bubo it is necessary to conduct subsidiary observations on a large quantity of animals and with a large number of implantations.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 01, 1968
- Accession Number
- AD0676341
Entities
People
- G. S. Uvahnenko
- N. N. Korganov
Organizations
- United States Army Biological Warfare Laboratories