COMPLEXES OF INFLUENZA VIRUS WITH ORGANIC BASES AND CATIONIC DETERGENTS
Abstract
The virus of influenza precipitates from solutions completely only with cationic detergents. Viruses, like higher proteins, form complex compounds with organic bases and cationic detergents. Stability of linkage of carboxyl groups of the virus micelle with organic bases and cationic detergents is not great, and these complexes more or less easily split in physiological solutions of salts. The search for antiviral chemotherapeutic agents must be directed along the road of search for compounds harmless for organisms, possessing cations that are very complex in structure, of high molecular weight, capable to combine stably with the carboxyl groups of the virus.
Document Details
- Document Type
- Technical Report
- Publication Date
- Sep 01, 1968
- Accession Number
- AD0676347
Entities
People
- M. I. Karlina
- V. I. Tovarnitskii
Organizations
- United States Army Biological Warfare Laboratories