THE ROLE OF CATECHOLAMINES AND SEROTONIN IN THE PROCESS OF ADAPTATION TO HIGH ALTITUDE.

Abstract

This work is relationed with the study of the catecholamines and serotonin in the process of adaptation to high altitude. The effects of hypoxia (12.85% O2 in N2) on the pulmonary artery pressure of dogs have been studied, as well as the variations in the levels of Serotonin and Catecholamines in the blood of the same artery. Hypoxia produced pulmonary hypertension in the dogs studied, and at the same time an increase in the level of Serotonin in the blood of the pulmonary artery was produced. The dogs reserpinized had hypertension pulmonary. This result is expounded in relation to a reflex vasoconstriction, which is mediated by Serotonin. (Author)

Document Details

Document Type
Technical Report
Publication Date
Sep 01, 1968
Accession Number
AD0676685

Entities

People

  • Arnoldo Medina
  • Gilberto Olava
  • Luis Utano

Tags

Communities of Interest

  • Materials and Manufacturing Processes

DTIC Thesaurus Topics

  • Altitude
  • Anatomy
  • Arteries
  • Biological Sciences
  • Blood
  • Cardiovascular Diseases
  • Cardiovascular System
  • Catecholamines
  • High Altitude
  • Hypertension
  • Pulmonary Hypertension
  • Serotonin

Fields of Study

  • Biology

Readers

  • Cardiovascular Physiology