ON THE CHEMICAL COMPOSITION OF THE ANTIGENIC SUBSTANCES of the agent of tularemia

Abstract

The conducted studies established that the antigenic complex of the tularemia microbe, by its chemical nature, significantly differs from the full antigens of Buaven, from the bacteria of the intestinal-typhus group, studied to this time. Two complicated complexes-fractions II and III- enter into the composition of the tularemia antigen. It was established that the latter complexes are separate components, firmly linked together. Thus, fraction II represents a stable complex, consisting of polysaccharides, albumin and nucleic acid, and fraction III-stable polysaccharides, albuminous complex. The albuminous components of the said fractions contain at least 17 similar amino- acids. The presence of qualitatively different polysaccharides in these fractions indicates: either two antigens, or one with various determinant groups.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 1968
Accession Number
AD0676984

Entities

People

  • G. K. Shipitsina

Organizations

  • United States Army Biological Warfare Laboratories

Tags

Communities of Interest

  • C4I

DTIC Thesaurus Topics

  • Acetic Acid
  • Acids
  • Amino Acids
  • Bacteria
  • Carbohydrates
  • Chemical Composition
  • Nucleic Acids
  • Polysaccharides
  • Tickborne Diseases
  • Translations
  • Two Dimensional

Readers

  • Immunology
  • Molecular and Cellular Biochemistry

Technology Areas

  • Biotechnology