EXPERIMENTAL MATERIAL ON THE ETIOLOGY OF THE AUTUMNAL FORM OF ENCEPHALITIS, REPORT 2

Abstract

The report states that 48 strains of virus have been isolated from patients and people who died from the disease. These strains and all strains tested in all experiments are identical (biologically and serologically) to Japanese encephalitis. Vectors were ascertained to be the Culex pipiens and Culex tritaeniorhynchus. This coincides with reports from Japan on the vectors of encephalitis. Humans and animals were also named as vectors of the virus, ailing or healthy. Reports of the epidemic in Tokyo in 1938 stated (according to this author) that humans and horses had a high titer of antibodies of encephalitis, and figures are 86% in humans, 98% in horses, 86% in cows and 87% in pigs. Tests on humans and birds, not infected or having been infected, were made to determine their virus capacity at the time of this epidemic; blood from humans was blended (three blood samples) and injected into mice (white). An experimental encephalitis developed. The strain was identical to that of infected humans. Only one strain survived a 3 month storage in 50% glycerine. Strains were easy to handle and filtered nicely.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 1968
Accession Number
AD0676987

Entities

People

  • A. K. Shubladze

Organizations

  • United States Army Biological Warfare Laboratories

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Animals
  • Antibodies
  • Birds
  • Dilution
  • Diseases And Disorders
  • Encephalitis
  • Etiology
  • Infection
  • Materials
  • Neutralization
  • Virus Diseases
  • Viruses
  • Wound Infections

Fields of Study

  • Biology

Readers

  • Immunology
  • Vector-Borne Disease and Entomology