STUDY OF THE ANTIGENIC COMPOSITION OF SOME F. TULARENSIS STRAINS. REPORT 2. COMPARATIVE ANTIGENIC COMPOSITION OF VIRULENT AND AVIRULENT BACTERIA

Abstract

The presence of 12 antigenic components in avirulent strain No 21/400 of F. tularensis was demonstrated by the reaction of precipitation in gel. Using the same method 12 antigenic components identical with those of the avirulent strain and an additional one, A antigen, were demonstrated in a virulent (No 128) and vaccine (No 15) strains. A antigen is situated on the surface (in the capsule) and in the bacterial cell wall. Large flake agglutination in the presence of tularemia is related to the presence of A antigen in the bacterial cells and of the corresponding A antibodies in the serum. The virulent (No 128) and avirulent (No 21/400) strains have five thermostable and seven thermolabile antigeni components in common, while the virulent strain contains, in addition, thermostable A antigen.

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Document Details

Document Type
Technical Report
Publication Date
Nov 29, 1967
Accession Number
AD0677266

Entities

People

  • V. V. Sukhar

Organizations

  • United States Army Biological Warfare Laboratories

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Absorption
  • Absorption Spectra
  • Agglutination
  • Antibodies
  • Bacteria
  • Biology
  • Cells
  • Cellular Structures
  • Electron Microscopes
  • Electrons
  • Epidemiology
  • Experimental Data
  • Microbiology
  • Precipitation
  • Thermostability
  • Tickborne Diseases

Fields of Study

  • Biology

Readers

  • Immunology

Technology Areas

  • Biotechnology