INVESTIGATION OF BOTULIN TOXINS AND TOXOIDS WITH THE GEL FILTRATION METHOD. REPORT 2. SEPARATION OF CRUDE TYPE A BOTULIN TOXINS VIA FILTRATION THROUGH SEFADEX G-200 GEL

Abstract

Toxin molecules in the type A botulin toxin vary as to size. The basic toxic activity in crude preparations is bound with protein of molecular weight over 200,000; one third -- with proteins of molecular weight close to 160,000, and about 1% -- with proteins of molecular weight close to 65,000.

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Document Details

Document Type
Technical Report
Publication Date
Nov 20, 1967
Accession Number
AD0677653

Entities

People

  • I. M. Mikhailova
  • V. B. Freiman
  • V. K. Golshmid

Organizations

  • United States Army Biological Warfare Laboratories

Tags

DTIC Thesaurus Topics

  • Albumins
  • Amino Acids
  • Cardiovascular Physiological Processes
  • Dissociation
  • Filtration
  • Fractionation
  • Gastrointestinal Tract
  • Globulins
  • Intact Stability
  • Molecular Weight
  • Molecules
  • Nitrogen
  • Proteins
  • Serum Globulin
  • Toxicity

Readers

  • Microbial Pathology