MOLECULAR MECHANISMS OF ALKYLATION OF A BIOLOGICAL SYSTEM

Abstract

Among chemical mutagens the group of alkylating compounds occupies a singular position both in intensity of action on the mutagenesis of various organisms, as well as in diversity of structure of functional centers. Investigation of the molecular mechanism of action of mutagens has a direct bearing on a most crucial problem in genetics -- directed hereditary variability. The report examines the fundamentals of the process underlying formation of mutations from the chemical vantage point.

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Document Details

Document Type
Technical Report
Publication Date
Oct 25, 1967
Accession Number
AD0677842

Entities

People

  • Yu. E. Bartoshevich

Organizations

  • United States Army Biological Warfare Laboratories

Tags

DTIC Thesaurus Topics

  • Cells
  • Chemical Synthesis
  • Chemistry
  • Chromosomes
  • Fungi
  • Genetics
  • Ionization
  • Microbiology
  • Nitroso Compounds
  • Organic Chemistry

Fields of Study

  • Chemistry

Readers

  • Molecular and genetic basis of cancer.
  • Organic Chemistry
  • Theoretical Analysis.

Technology Areas

  • Biotechnology