HYDRATION OF MACROMOLECULES IN THE NATIVE AND DENATURED STATES

Abstract

The question of the reciprocal influence of macromolecules and the water layers adjacent to them is examined. The Kauzmann and Klotz models are compared. Experimental calorimetric findings on macromolecule hydration are cited. The denaturation change of hydration is studied. It is demonstrated that hydration of denatured macromolecules is greater than hydration of native molecules, which speaks in favor of Kauzmann's model.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Oct 26, 1967
Accession Number
AD0677843

Entities

People

  • G. M. Mrevlishvili
  • P. L. Privalov

Organizations

  • United States Army Biological Warfare Laboratories

Tags

Communities of Interest

  • Advanced Electronics

DTIC Thesaurus Topics

  • Absorption
  • Albumins
  • Amino Acids
  • Biophysics
  • Biopolymers
  • Chemistry
  • Electrical Conductivity
  • Electrical Properties
  • Ionizing Radiation
  • Macromolecules
  • Magnetic Resonance
  • Molecules
  • Nuclear Magnetic Resonance
  • Nucleic Acids
  • Proteins
  • Specific Heat
  • X Rays

Fields of Study

  • Chemistry

Readers

  • Materials Science and Engineering.
  • Molecular and Cellular Biochemistry
  • Theoretical Analysis.