ACUTE MORTALITY OF MICE AND RATS EXPOSED TO MIXED GAMMA-NEUTRON RADIATIONS OR TO X RAYS
Abstract
Mortality data for C57BL mice and Sprague-Dawley rats were collected as a part of the program to biologically characterize AFRRI-TRIGA reactor radiations and to provide reference information for future studies. Unilateral whole body exposures to mixed gamma-neutron radiations from the reactor or to 250 kVp x rays were carried out over a range of midline tissue doses from 370 to 875 rads. The 30-day median lethal doses were calculated to be 589 and 432 rads for mice exposed to the x rays and to the reactor radiations, respectively. The corresponding values for the rat exposures were 740 and 434 rads. Using the LD50/30 values as the end points for comparison, the reactor radiations were 1.4 and 1.7 times more effective in mice and rats, respectively, than were the x rays. The survival times of the mice and rats exposed to reactor radiations were significantly less than those of the animals exposed to similar doses of x rays.
Document Details
- Document Type
- Technical Report
- Publication Date
- Apr 01, 1968
- Accession Number
- AD0678365
Entities
People
- L. J. Seigneur
- R. E. Stanley
- T. A. Strike
Organizations
- Armed Forces Radiobiology Research Institute