THE BIOLOGICAL CHARACTERISTICS OF INAGGLUTINABLE CULTURES OF BRUCELLA MELITENSIS

Abstract

The inagglutinable cultures of Br. melitensis were studied that were typical with respect to their morphological and cultural aspects and also with respect to their ability to reduce aniline dyes. A distinctive feature was the presence of positive signs of dissociation and the loss of the ability to be agglutinated by a specific antibrucellosis serum. With respect to these aspects they were identical to the cultures described by Drozhevkina as V-cultures. The inagglutinable Brucella cultures had lowered virulence in various degrees (in comparison with the agglutinable cultures). The somewhat large residual virulence of some of the inagglutinable strains (No 512, 705, 65) could be explained by the presence in the population of a small percentage of agglutinable undissociated species, the predominant settlement of which in the organism of the guinea pigs was the basis for the development of infection.

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 1968
Accession Number
AD0678902

Entities

People

  • N. N. Ostrovskaya

Organizations

  • United States Army Biological Warfare Laboratories

Tags

DTIC Thesaurus Topics

  • Animals
  • Brucellosis
  • Cells
  • Chemical Composition
  • Dissociation
  • Infection
  • Lagomorphs
  • Lethal Dosage
  • Lymph Nodes
  • Lymphatic System
  • Rodents
  • Russian Language
  • Secretion
  • Virulence
  • Wound Infections

Fields of Study

  • Biology

Readers

  • Approximation Theory.
  • Chemistry (specifically Chemical Fluorescence)
  • Immunology