THE ISOLATION OF THE BRUCELLOSIS PATHOGEN FROM THE EYES OF GUINEA PIGS FOLLOWING EXTRAOCULAR INFECTION
Abstract
Conclusions of the experiments are the following: The bacteriological investigation of conjunctival secretion merits wide usage in the complex laboratory diagnosis of brucellosis infection in the early stages after the infection of man and animals. It is possible to isolate Brucella organisms from the eyes with experimental endogenous brucellosis ailments of the keratoiridocyclite type by means of culturing in artificial nutrient media and infecting the animals; in this, as the time from the beginning of the inflammatory process in the eye and from the moment of infection increases, this possibility is lessened. The formation and duration of the resistance of the eye tissue to Brucella contamination are more reliably provided by subcutaneous vaccination with Brucella organisms of strain Br. abortus bovis 19 than by enteral and intranasal vaccination with the same strain.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 01, 1968
- Accession Number
- AD0678906
Entities
People
- F. I. Usmanova
- L. G. Lopatukhina
- V. M. Kiseleva
Organizations
- United States Army Biological Warfare Laboratories