METHOD OF PROCESSING BACTERIOLOGICAL PREPARATIONS WITH fluorescent antibodies

Abstract

The work deals with preparation, fixation and staining of bacteriological preparations with fluorescent antibodies (direct and indirect methods). The authors' investigations have demonstrated that the temperature regimen and the duration of smear staining by means of fluorescent antibodies are important factors, conditioning the intensity and specificity of microbial cells fluorescence. The composition of the washing liquids and the methods of fixation of the preparations had no essential effect on the capacity of bacterial cells to be stained with specific fluorescent antibodies.

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 1968
Accession Number
AD0678908

Entities

People

  • I. O. Dashkevich
  • I. V. Osipova
  • S. I. Dyakov

Organizations

  • United States Army Biological Warfare Laboratories

Tags

Communities of Interest

  • Materials and Manufacturing Processes

DTIC Thesaurus Topics

  • Antibodies
  • Biological Staining And Labeling
  • Blood Proteins
  • Buffers (Chemistry)
  • Chemistry
  • Fluorescence
  • Gamma Globulin
  • Globulins
  • Immune Serums
  • Immunoglobulins
  • Intensity
  • Low Temperature
  • Luminescence
  • Microorganisms
  • Proteomics
  • Serum Globulin
  • Vaccines

Fields of Study

  • Biology

Readers

  • Immunology

Technology Areas

  • Biotechnology
  • Biotechnology - Cancer Biotech