EFFECT OF TYPE B BOTULINAL TOXIN ON THE LEVEL OF PYRUVIC ACID IN TISSUES OF GUINEA PIGS,

Abstract

Intramuscular injection of 100 MLD of the botulinal toxin type B to guinea pigs evoked 20 minutes later some changes in their level of pyruvic acid in the tissues of the central nervous system, in the muscles and in the blood; they varied according to the intensity and trend. The quantity of pyruvic acid decreased in myelencephalon and in the spinal cord. The index of pyruvic acid virtually did not change in the cerebral hemispheres. An accumulation of pyruvic acid occurred in the muscles and in the blood. (Author)

Document Details

Document Type
Technical Report
Publication Date
Jul 01, 1968
Accession Number
AD0678938

Entities

People

  • Z. P. Pak

Organizations

  • United States Army Biological Warfare Laboratories

Tags

DTIC Thesaurus Topics

  • Acids
  • Anatomy
  • Biological Sciences
  • Brain
  • Central Nervous System
  • Hemispheres
  • Intramuscular Injections
  • Nervous System
  • Pyruvic Acid
  • Rodents
  • Spinal Cord

Fields of Study

  • Medicine
  • Psychology

Readers

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  • Microbial Pathology