MASS STUDIES OF THE IMMUNOLOGICAL EFFECT OF VACCINATION AGAINST TULARAEMIA,
Abstract
Dermal tularin is suitable for diagnostic purposes and also for assessing the effectiveness of vaccination and the duration of immunity in vaccinated persons (by the presence of allergic reactivity in the skin). Side effects are observed considerably less often in the dermal tularin test than after the injection of intradermal tularin or live tularaemia vaccine. The simplicity of the technique of skin testing and the rapid attaining of results (after 24--48 hr) are undoubted advantages of this method over revaccination. Unlike vaccination the skin test with tularin can be carried out at the same time as other inoculations (not dermal) are given. These findings show that dermal tularin is a preparation which by virtue of its diagnostic qualities and weak reactivity completely replaces intradermal tularin and live tularaemia vaccine, and which should be put into wide practical use in the testing of the immunological effectiveness of vaccination against tularaemia. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 1957
- Accession Number
- AD0680377
Entities
People
- V. S. Silchenko
Organizations
- United States Army Biological Warfare Laboratories