THE QUESTION OF THE INTENSITY OF IMMUNITY IN EXPERIMENTAL ANIMALS WHICH RECOVERED AFTER TREATMENT WITH STREPTOMYCIN AND SERUM

Abstract

In guinea pigs infected with plague and treated with streptomycin a postinfection immunity is not developed. The experimental animals which had recovered through treatment with a refined, concentrated gamma-globulin fraction of antiplague serum proved to be immune to a re-inoculation with the specific culture. Taking into consideration the therapeutic properties and the data concerning the different mechanism of action possessed by streptomycin and by the gamma-globulin fraction of antiplague serum, one should consider their joint use as expedient for therapeutic purposes.

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 1968
Accession Number
AD0680488

Entities

People

  • A. L. Kartashova
  • E. L. Semenova
  • G. F. Abramova

Organizations

  • United States Army Biological Warfare Laboratories

Tags

Communities of Interest

  • Materials and Manufacturing Processes

DTIC Thesaurus Topics

  • Active Immunity
  • Adaptive Immunity
  • Animals
  • Anti-Bacterial Agents
  • Bacteria
  • Central Asia
  • Gamma Globulin
  • Globulins
  • Immunity
  • Infection
  • Intensity
  • Laboratory Animals
  • Rodents
  • Scientific Research
  • Thorax
  • Wound Infections

Fields of Study

  • Biology
  • Medicine

Readers

  • Immunology