CONTEMPORARY STATE OF EXPERIMENTAL INVESTIGATIONS ON THE SPECIFIC PROPHYLAXIS OF COCCIDIOIDOMYCOSIS

Abstract

Live vaccines from virulent, weakly virulent, and avirulent strains of C. immitis created an intense immunity in experimental animals. Here the optimum immunizing doses changed reversely proportional to the degree of virulence of the strain being tested. However, even live vaccines did not exclude as far as possible the appearance of histomorphological or apparent focal changes of weak or moderate severity in the lungs during subsequent respiratory infection or in the organs of the peritoneal cavity - following subsequent intraperitoneal infection with lethal doses of a virulent strain of this fungus.

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Document Details

Document Type
Technical Report
Publication Date
Nov 01, 1968
Accession Number
AD0680493

Entities

People

  • S. L. Borodko

Organizations

  • United States Army Biological Warfare Laboratories

Tags

DTIC Thesaurus Topics

  • Animals
  • Bacterial Infections And Mycoses
  • Diseases And Disorders
  • Immunity
  • Infection
  • Laboratory Animals
  • Lethal Dosage
  • Maryland
  • Mycoses
  • Preventive Medicine
  • Recovery
  • Translations
  • Wound Infections

Fields of Study

  • Biology

Readers

  • Immunology

Technology Areas

  • Biotechnology