EXPERIMENTAL STUDY OF ACUTE AND CHRONIC INJURY TO RENAL TUBULES.
Abstract
The work carried out was multifaceted, dealing with the many factors concerned in acute and chronic injury to renal tubules. In view of the fact that most tubular lesions are the consequence of vascular impairment, many of the studies involved an examination of the behavior of arteries, arterioles and glomeruli in the face of different stimuli. The juxtaglomerular apparatus is intimately concerned in the regulation of blood flow and experiments were carried out to shed light on this structure. The factors concerned in the stimulus for hyperplasia of the juxtaglomerular apparatus were studied to test the validity of the notion that the tonicity of the filtrate acting on the macula densa is of importance. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Nov 01, 1968
- Accession Number
- AD0680948
Entities
People
- F. K. Mostofi
- Robert H. Heptinstall
Organizations
- Johns Hopkins University