EARLY EFFECTS OF 150-MEV PROTON IRRADIATION IN RHESUS MONKEYS

Abstract

Rhesus monkeys were exposed to 150-Mev proton irradiation at 11 rads per minute. After exposure, the animals were observed for clinical changes and mortality. Hematologic studies were performed up to 80 days after exposure. On the basis of acute median lethal dose, mean survival time, clinical observations, and blood cell depression, an RBE of unity was assigned when comparing the 150-Mev proton exposures with 2-Mev x-ray exposures. A decrease in median lethal dose was noted with lowered dose rate when proton exposures at 57 rads per minute and 11 rads per minute were compared.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 1968
Accession Number
AD0681465

Entities

People

  • Alan M. Siegal
  • Joseph E. Traynor

Organizations

  • United States Air Force School of Aerospace Medicine

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Air Force Facilities
  • Animals
  • Blood
  • Blood Cells
  • Cells
  • Dose Rate
  • Dosimetry
  • Factor Analysis
  • Ions
  • Lethal Dosage
  • Monkeys
  • Proton Beams
  • Radiation
  • Rhesus Monkeys
  • Survival
  • Test And Evaluation
  • X Rays

Fields of Study

  • Medicine
  • Physics

Readers

  • Nuclear and Radiation Engineering.
  • Toxicology/Environmental Toxicology