THE SPREAD OF LEPTOSPIRAE IN THE BODY AND ANTIBODY FORMATION IN EXPERIMENTALLY INDUCED LEPTOSPIROSIS IN IRRADIATED ANIMALS

Abstract

In the animals inoculated with the pathogen of leptospirosis 2 to 24 hours post irradiation by X-rays, the antibody production was suppressed, but upon inoculation 48 hours after irradiation, the formation of antibodies was completely absent. The leptospiremic phase of the infection lasts longer in the irradiated animals than in the control animals. Thus, the longer the duration of the leptospiremia the more intensely the antibody formation is repressed. The length of the occurrence of leptospirae in the organs of the mice inoculated after irradiation is greater than the control animals that were only inoculated.

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 1968
Accession Number
AD0682553

Entities

People

  • R. V. Petrov

Organizations

  • United States Army Biological Warfare Laboratories

Tags

Communities of Interest

  • Materials and Manufacturing Processes

DTIC Thesaurus Topics

  • Animals
  • Antibodies
  • Infection
  • Inoculation
  • Lagomorphs
  • Leptospirosis
  • Pathogenic Bacteria
  • Production
  • Rodents
  • Wound Infections
  • X Rays

Fields of Study

  • Biology

Readers

  • Immunology