THE PROPHYLACTIC AND THERAPEUTIC ACTION OF SOMATOTROPIC HORMONE IN RADIATION AFFECTION

Abstract

STH facilitates the maintenance of weight in animals irradiated with sublethal and minimum lethal doses of X-rays, but does not increase their survival times. Joint administration of STH, DOCA and salt solution exerts a significant influence on the weight of the animals and hastens their death. The administration of STH prior to irradiation with sublethal doses of X-rays exhibits a definite protective effect. In irradiated animals, STH increases the weight of the adrenals and normalizes the absolute weight of the endocrine glands and internal organs. In control rats, the weight of the adrenals, thyroid and testes is increased in comparison with that of the irradiated animals.

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 1968
Accession Number
AD0682568

Entities

People

  • A. E. Rabkina
  • D. E. Grodzenskii
  • D. E. Grodzenskiy
  • E. R. Bagramyan

Organizations

  • United States Army Biological Warfare Laboratories

Tags

Communities of Interest

  • Materials and Manufacturing Processes

DTIC Thesaurus Topics

  • Adrenal Gland Diseases
  • Amino Acids
  • Animals
  • Body Weight
  • Drinking Water
  • Endocrine Glands
  • Glands
  • Ionizing Radiation
  • Lethal Dosage
  • Radiation
  • Radiation Sickness
  • Rodents
  • Saline Solution
  • Survival
  • Tissues
  • X Rays

Readers

  • Nuclear and Radiation Engineering.
  • Toxicology/Environmental Toxicology