PREPARATION AND PROPERTIES OF BOVINE, MONKEY, AND RAT GROWTH HORMONES

Abstract

Growth hormones were obtained from bovine, green marmoset, and rat pituitaries by various methods. They were homogeneous based on data from ultracentrifugation and electrophoresis. The somatotropins from the green marmoset and rats have a similar amino acid composition; phenylalanine is the N- and C-terminal amino acid of these hormones. The molecular weight of rat and green marmoset STG equals respectively 27,000 and 30,000. In spite of significant differences in the physico-chemical properties, preparations of bovine, monkey, and rat growth hormones exert a similar biological action on hypophysectomized rats.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Nov 04, 1968
Accession Number
AD0683010

Entities

People

  • T. M. Chulkova
  • V. N. Orekhovich

Organizations

  • United States Army Biological Warfare Laboratories

Tags

DTIC Thesaurus Topics

  • Acetic Acid
  • Amino Acids
  • Chemical Properties
  • Citric Acid
  • Coefficients
  • Diffusion Coefficient
  • Immune Serums
  • Molecular Weight
  • Proteins

Fields of Study

  • Biology

Readers

  • Molecular and Cellular Biochemistry
  • Toxicology/Environmental Toxicology