EXPERIMENTAL AIRBORNE INFECTION WITH LISTERIA OF SOME SPECIES OF ANIMALS
Abstract
White mice and guinea pigs are extremely sensitive to listerellosis in the airborne method of infection and less sensitive to the subcutaneous and oral methods. Where the causative agents is introduced per os or subcutaneously, the majority of the mice die with the clinical manifestations of an affliction of the central nervous system. Excretion of listeria by the sick and convalescent guinea pigs occurs through the nasal discharge, urine and feces for a period of 40 24-hour periods, and by pigs up to the 8th 24-hour period after infection. Pigs become ill with listerellosis upon their infection by an aerosol and remain carriers of listeria as long as 75 24-hour periods after recovery. The frequent detection of listeria in the brain tissue of the experimental animals, without a visible clinic of the disease, indicated a prolonged carrying, and the presence of a hidden form of the listerellal infection under natural conditions, that should be taken into consideration in a bacteriological diagnosis and in an analysis of an epizootic and epidemiological situation.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 01, 1968
- Accession Number
- AD0683014
Entities
People
- V. I. Popov
Organizations
- United States Army Biological Warfare Laboratories