A CONTRIBUTION TO THE INVESTIGATION OF BARRIER FIXING MANIFESTATIONS OF IMMUNITY IN DYSENTERY AND CHOLERA
Abstract
The cholera vibrio and Flexner's dysenteric bacteria, in a subcutaneous inoculation of white mice, manifest a sharply expressed invasive capacity: within a few minutes after inoculation these bacterial species fill the local lymphatic barrier, break through it and penetrate into the internal organs and blood of the animals. The invasive properties of the Shiga bacteria, as compared to the cholera vibriones and Flexner's bacteria, are sharply retarded. In a subcutaneous inoculation of mice that were immunized with cholera and Flexner vaccines the corresponding pathogens did not penetrate deeply into the organism and, as a rule, were fixed at the first lymphatic barrier. The data obtained in this investigation opens the door to a systematic study of the antibacterial barrier fixing manifestations of immunity in cholera, and Flexner dysentery.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 01, 1968
- Accession Number
- AD0683015
Entities
People
- E. M. Slavskaya
- V. M. Berman
Organizations
- United States Army Biological Warfare Laboratories