HUMAN SERUM ANTI-GLOBULINS AND IMMUNIZATION.
Abstract
Human serum anti-globulins (AGs) of differing reactivities were studied in subjects who had received intensive immunization over a period of 8 weeks, and in persons who had been injected intramuscularly with hyperimmune gamma-globulin. A small percentage of the first group (intensive immunization) showed serum changes consisting of either the development or increase in titer in the latex fixation test (4 to 65), or the appearance 'de novo' of an atypical weak latex reactivity (3 of 65). Of interest was the observation that 'pepsin agglutinators' remained unaltered. The data was interpreted as indicating that neither limited quantities of I. M. gamma gloublin nor intensive immunization affected the serum AGs in most individuals, but a small number of subjects did respond with serum changes. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Dec 13, 1968
- Accession Number
- AD0684348
Entities
People
- Charles E. Shields
- Stephen D. Litwin
Organizations
- United States Army Medical Research Laboratory