A STUDY OF BLOOD pH, SERUM POTASSIUM CONCENTRATION, AND STRESS IN THE SQUIRREL MONKEY (SAIMIRI SCIUREUS),
Abstract
Serum potassium concentration in the squirrel monkey is elevated as compared to that of other commonly used laboratory animals. This study was designed to determine if the levels observed for the potassium ion are related to a change in pH. Related parameters of serum CO2 and pCO2 are reported. Data accumulated from the study of biochemical parameters in the squirrel monkey cannot be rationalized in terms of in vivo buffer systems. Serum potassium and CO2 appear to be related to altered pH, since low pH values were found in conjunction with low CO2 and high potassium. Stress brought about by restraint during blood collection was found to significantly alter the pH and potassium when these values were compared with those from tranquilized and anesthetized squirrel monkeys which were used as controls. The squirrel monkey appears to present an extreme stress response and thus may be a highly desirable biological system in which to elucidate those in vivo changes associated with stress. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Dec 01, 1968
- Accession Number
- AD0684781
Entities
People
- Albert E. New
- Thomas E. Wheeler
Organizations
- Naval Aerospace Medical Institute