STUDIES ON LEPTOSPIROSIS IN THAILAND, WITH SPECIAL REFERENCE TO THE EPIDEMIOLOGY, PATHOLOGY AND CLINICAL ASPECTS, AND ITS RELATION TO THE ANIMAL RESERVOIR HOSTS
Abstract
Epidemiological study of suspected cases of leptospirosis in 39 provincial hospitals in Thailand during January 1968 - December 1968 revealed 197 positives out of 1,377 cases (14.3%). Common Serogroups were L. icterohemorrhagiae, L.autumnalis and L.wolffii. However, in Bangkok Hospitals leptospirosis bataviae was common. Annual variation of human leptospirosis in Thailand (residual antibodies survey) was studied for the third consecutive year and the results indicated that the incidence was slightly increased (from 4% to be 6% and 9% respectively). Surveys of leptospiral antibodies in Umong Canton (an epidemic area near Chiengmai Province) revealed that the area was still considered to be an endemic area of leptospirosis. The correlation studies at Pitsanuloke Province enabled the author to find out an endemic area and revealed five leptospiral serogroups were prevalent in Pitsanuloke Province. The dried blood filter paper method was experimentally studied and the results revealed that it was reliable and practical for diagnosis of the disease in suspected cases from provincial areas. In animal experiments, L.javanica (Bangkok) L. icterohemorrhagiae (Uttaradith) and L.akiyami A (Uthaidanee) were all proved to be of high virulence to hamsters. There were at least 20 serotypes of pathogenic leptospirae so far discovered from Thailand and belong to 12 serogroups.
Document Details
- Document Type
- Technical Report
- Publication Date
- Feb 14, 1969
- Accession Number
- AD0684960
Entities
People
- Bundham Sundharagiati