AT SEFEN - A NEW PREPARATION FOR TREATING MENTAL AND NERVOUS DISORDERS,

Abstract

The hydrochloride of the dimethylaminoethyl ester of n-chlorphenoxyacetic acid was synthesized in the Soviet Union under the name 'At Sefen'. This drug, which has been used abroad under the name Lucidril, Centrophenoxine, Meclofenoxate, etc., is characterized as a unique psychocorticotonic agent with a regulating effect on the central nervous system. Soviet research has shown it to be effective as a stimulating agent in asthenic conditions of neurotic origin, in astheno-hypochondriac and hypochondriac syndromes of neurosis-like and periodic schizophrenia, in apathetic and depressive states related to cerebral arteriosclerosis or traumatic brain damage. Positive results have also been achieved in treatment of involutional melancholia, in the presence of vegetative disturbances, anxieties, apathy, sluggishness, and depressive-apathetic state. The therapeutic effect of the drug is not immediate, but may take a month or more. (Author)

Document Details

Document Type
Technical Report
Publication Date
Apr 17, 1969
Accession Number
AD0686141

Entities

People

  • S. S. Lieberman

Organizations

  • United States Army Foreign Science and Technology Center

Tags

DTIC Thesaurus Topics

  • Brain Injuries
  • Central Nervous System
  • Diseases And Disorders
  • Mental Disorders
  • Nervous System
  • Nervous System Diseases
  • Neurodevelopmental Disorders
  • Neurotic Disorders
  • Schizophrenia
  • Ussr
  • Vascular Diseases
  • Wounds And Injuries

Fields of Study

  • Medicine
  • Psychology

Readers

  • Cardiovascular Physiology
  • Library and Information Science/ Studies, Southeast Asia Studies, Bibliography of Vietnam and Lao Studies.
  • Psychological Intervention/Treatment for Stress, Anxiety, PTSD, and Related Emotional and Cognitive Health Symptoms.