INSULIN-INHIBITORY FACTOR IN HUMAN BLOOD: ROLE IN THE CHARCOAL RADIOIMMUNOASSAY.
Abstract
The insulin-inhibitory factor in human blood was studied. The results of a recovery study with a single-antibody assay (the charcoal radioimmunoassay) were compared to those with a two-antibody assay to determine whether inhibition occurred between insulin and the first antibody or between the first and the second antibody. The single-antibody assay did not show an insulin-inhibitory factor, but the two-antibody radioimmunoassay did show an inhibitor. The inhibitor must therefore act between the anti-human (gamma globulin) antibody and the anti-insulin antibody to block the reaction. The exact nature of the inhibitor is as yet unknown. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Dec 01, 1968
- Accession Number
- AD0686731
Entities
People
- Donald F. Logsdon Jr.
- James F. Green
Organizations
- United States Air Force School of Aerospace Medicine