THE FORMATION OF ANTIBIOTIC-RESISTANT STRAINS OF S. TYPHI AND SH. DYSENTERIAE FLEXNERI UNDER CONDITIONS OF CONTINUOUS CULTURING,
Abstract
Five strains of typhoid bacilli and five strains of dysentry flexneri bacilli were grown in continuous culture with increment doses of mycerin and streptomycin. Data are presented on antibiotic concentrations required for the lowest and highest resistance of each strain under various conditions. Antibiotic resistance developed more rapidly in continuous culture than in the control stationary cultures, and variants were observed with modified antigentics and enzymic properties. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Apr 09, 1969
- Accession Number
- AD0688053
Entities
People
- A. N. Kovalevskaya
Organizations
- United States Army Foreign Science and Technology Center