SPECIFIC PROPHYLAXIS HOOF AND MOUTH DISEASE
Abstract
Specific prophylaxis by inoculating animals was established as early as 1902. Research by other scientists concluded that it was more economical to prevent hoof and mouth disease with medical than with prophylactic agents. Danish researchers prepared the aphthous 'GOAL' vaccine which was created against civirus types 'A' and 'O' and lengthened the period from two to three months. Later it became possible to mass reproduce virus of hoof and mouth disease in the mucous of the tongues of cattle. A vaccine resulting from the Frenkel method was highly effective and protected the animals from 4 to 5 months, but on re-evaluating the series it was less effective than the vaccine from a natural aphthous virus. Continuance of immunity was dependent on the individual characteristics of the animals and the quality of vaccine. The intensity of immunity usually depended on the immunization strains of virus manufactured and often also on the type of implementation and method of vaccine preparation.
Document Details
- Document Type
- Technical Report
- Publication Date
- May 02, 1969
- Accession Number
- AD0690485
Entities
People
- A. A. Syusyukiy
- E. V. Andreyev
- N. V. Likhachev
- V. N. Onufriyev
Organizations
- United States Army Foreign Science and Technology Center