TEMPERATURE DEPENDENCE OF VENOM PHOSPHOLIPASE A AND RELATED HAEMOLYSIS

Abstract

Phospholipase A activity of the venom of Crotalus adamanteus was found to increase by a factor of two for every 10C. increase in temperature. A percentage of haemolysis of red cells by lysolecithin produced by phospholipase A occurred at two times lower lysolecithin concentration for every 10C. decrease in temperature. Under all conditions, percent lysis increased with decreasing the temperature in a complex reaction mixture would be expected to produce an instantaneous increase in the percentage of cells lysed.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Jun 01, 1969
Accession Number
AD0690800

Entities

People

  • Charles R. Wilson
  • James G. Wetmur
  • William P. Schane

Organizations

  • United States Army Aeromedical Research Lab

Tags

DTIC Thesaurus Topics

  • Biomedical Research
  • Blood
  • Blood Vessels
  • Body Fluids
  • Coefficients
  • Dilution
  • Enzyme Kinetics
  • Fluids And Secretions
  • Hemic And Immune Systems
  • Indicator Dyes
  • Low Temperature
  • Measurement
  • Plant Extracts
  • Snake Bites
  • Sodium Hydroxide
  • Temperature Coefficients
  • Tissues

Fields of Study

  • Biology

Readers

  • Mathematics or Statistics
  • Molecular and Cellular Biochemistry
  • Superconducting Magnet Technology