PHYSICOCHEMICAL TISSUE CHANGES FOLLOWING IRRADIATION.

Abstract

Whole body irradiation (WB1) produces scopal and abscopal effects in albino rats. Primary scopal events are deploymerization of interstitial substance (1SW) mucoprotein, with increases in acid, free water and in destruction of mobile cells of 1 SW (erythrocytes; leukocytes; histiocytes; plasma cells). Membranes resistant to water perfusion form in 1SW, and may proceed to frank fibrosis, depending upon quality and quantity of WB1. Abscopal effects follow dissemination of scopal physiocochemical agents, and affect, particularly, brain, heart, lung, kidney, and gastro-intestinal tract. Iatrogenic alteration of the 1SW is possible, for reduction of scopal effects of WB1, hence, abscopal perfusion. Results of our experiences with these alterations are presented. (Author)

Document Details

Document Type
Technical Report
Publication Date
Aug 01, 1969
Accession Number
AD0690855

Entities

People

  • B. L. Reynolds

Tags

DTIC Thesaurus Topics

  • Anatomy
  • Biological Sciences
  • Blood
  • Cells
  • Cells (Biology)
  • Erythrocytes
  • Fibrosis
  • Hemic And Immune Systems
  • Leukocytes
  • Macrophages
  • Membranes
  • Perfusion
  • Tissues
  • Whole Body Irradiation

Readers

  • Immunology
  • Immunology and Pathology
  • Maritime and Naval Warfare Studies