CHANGES IN ENZYMATIC AND CELLULAR ACTIVITY OF THE BLOOD: RESPONSE TO MAXIMAL EXERCISE AND INGESTION OF FOOD,
Abstract
Many investigators have studied the effect of muscular exercise on serum enzymes. An elevation in transaminase values occurs routinely with exercise and lasts approximately one hour unless significant muscle damage takes place; then elevation may persist several days. The post-exercise transaminase response is accentuated in untrained and/or deconditioned subjects. Even at rest, there is an indication that serum glutamic oxalacetic transaminase (SGOT) and serum glutamic pyruvic transaminase (SGPT) levels are inversely related to physical fitness. Muscular exercise affects primarily agranulocytic cellular elements of the blood, as studied in normal subjects. Fifteen men with an average age of 30 years were given a maximal performance running test to evaluate the exercise induced changes. Venous blood samples were obtained while the subjects were fasting and before and after the run. There were significant differences between pre-run and post-run levels of SGOT, SGPT and leukocyte responses; SGPT responded less to exercise than SGOT. Cellular components tended to follow enzyme changes, and the increase in lymphocytes was more pronounced than in neutrophils. Fasting and food ingestion, which also affected enzyme levels, were significant only for SGOT levels. Cellular elements and sedimentation rates showed no such effect. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 01, 1969
- Accession Number
- AD0693570
Entities
People
- Dominic Criscuolo
- George O. Gey Jr.
- Kenneth H. Cooper