THE STUDY AND COMPARISON OF THE ANTIGENIC STRUCTURE OF THE PRIMATE MALARIAS.
Abstract
Each primate plasmodium, simian and human, contains a series of protein components, some of which are precipitinogens. Such plasmodia, like the fowl- and rodent-plasmodia, are capable of being analysed by methods of diffusion in gel and by disc electrophoresis. Harvesting procedures leading to such analysis should be rigidly standardized in order to permit comparison of results. Lyophilized harvests should be prepared in vacuo. Host cell contaminants require to be identified in all such analytical procedures, and have not yet been fully identified. Analysis of the human plasmodia is greatly hampered by the fact that few teams are available for collecting antigen in the field, and that no other source of a continuing and relatively abundant supply of hyman plasmodia is yet available. Aotus monkeys may conceivably fill this gap if breeding colonies were to be established. If such analysis is to be carried out at this time, it is therefore recommended that field teams capable of harvesting plasmodia by a standardized procedure be invited to do so, in order to make a continuing supply of antigen available. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 01, 1969
- Accession Number
- AD0695675
Entities
People
- Avivah Zuckerman
- Dan Spira
- Joseph Hamburger
Organizations
- Hebrew University of Jerusalem