ADAPTATION TO CHRONIC HYPERBARIC OXYGEN PRESSURES.
Abstract
The report summarizes the research on the effects of hyperbaric medicine completed at the Pennsylvania State University. The progression of this research involved studies on renal function, blood flow, adrenocortical and sympatho-adreno-medullary (SAM) activity. The blood flow alterations indicated increased adrenocortical function. The adrenocortical function reaches its highest level just prior to death from oxygen poisoning. The excretion of catecholamine indicated an altered metabolism of epinephrine. It is noted that oxygen at high pressure results in the production of adrenochrome, adrenolutin and derivatives. These compounds are highly reactive and can account for the manifestations of oxygen toxicity. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Sep 17, 1969
- Accession Number
- AD0695822
Entities
People
- Rodney T. Houlihan
Organizations
- Pennsylvania State University