STUDY OF RECRUIDESCENT TYPHUS IN ISRAEL
Abstract
The study was undertaken in order to determine whether persons, once infected with epidemic typhus could subsequently suffer relapses, without clinical signs which could be detected by rises in antibody titer. Such cases of recrudescent typhus could presumably serve as sources of the microorganism in the interepidemic period and therefore be responsible for the initiation of new epidemics. The study was conducted among individuals most of whom had contracted epidemic typhus in Eastern Europe and immigrated to Israel after the Second World War. In enlisting volunteers for the study particular attention was paid to the reliability of their histories and the absence of murine typhus in their present environment. 294 individuals were thus selected. Interviews and sampling of bloods were conducted at regular two-three month's intervals. Six blood samples were obtained from 262 individuals and at least three samples from the rest. All sera obtained from any individual were examined in the same test for specific antibodies to epidemic typhus by complement-fixation and microagglutination.
Document Details
- Document Type
- Technical Report
- Publication Date
- Mar 01, 1969
- Accession Number
- AD0697744
Entities
People
- Marcus A. Klingberg
- Robert A. Goldwasser
- Wanda Klingberg
Organizations
- Israel Institute for Biological Research