SYNTHESIS AND CHARACTERIZATION OF 2-ETHYL-3-HEXANOL para-HYDROXYBENZOATE
Abstract
2-Ethyl-3-hexanol p-hydroxybenzoate was synthesized and characterized by infrared and ultraviolet spectroscopy and thin-layer (TLC) and gas-liquid chromatography (GLC). These methods proved the existence of stereoisomers and allowed the prediction of preferred conformations. The RR and SS enantiomers had a higher boiling point, a lower retention value on TLC, and were eluted faster on GLC than the RS and SR diastereoisomers. The ester exhibited antimicrobial activity against gram-positive bacteria and yeast, but not against gram-negative bacteria. The ester also exhibited sunscreen properties and was not toxic to animals.
Document Details
- Document Type
- Technical Report
- Publication Date
- Nov 01, 1969
- Accession Number
- AD0698026
Entities
People
- John W. Brown