TRANSPLANTATION ANTIGENS IN KERATOPLASTY. I. ISOLATION OF A SOLUBLE FRACTION WITH TRANSPLANTATION ANTIGEN ACTIVITY.
Abstract
A soluble protein fraction has been isolated from the cornea by simple aqueous extraction. This preparation possesses transplantation antigen activity as demonstrated by its ability to induce a specific sensitization resulting in the accelerated destruction of a corneal graft. The corneal antigen preparation is also capable of stimulating the production of humoral antibodies but the relationship between the transplantation immunity and the antibody response remains to be elaborated. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Sep 04, 1969
- Accession Number
- AD0699792
Entities
People
- Anthony J. Luzzio
- Howard M. Leibowitz
Organizations
- United States Army Medical Research Laboratory