CORNEAL ENDOTHELIUM IN VITRO: GROWTH INHIBITION AND STRUCTURAL CHANGES INDUCED BY HYDROCORTISONE.
Abstract
Corneal endothelium from young albino rabbits was grown in tissue culture in the presence of supraphysiologic concentrations of hydrocortisone. Examination of the cultured cells by light- and electron microscopy disclosed abnormalities in mitochondria, endoplasmic reticulum, cytoplasmic granules, and nuclear chromatin. Although hydrocortisone impaired outgrowth, a given number of corneal endothelial cells grown in the presence of hydrocortisone covered more surface area on the growth substrate than did an equal number of control cells. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Nov 01, 1969
- Accession Number
- AD0700727
Entities
People
- George M. Lowry
Organizations
- United States Air Force School of Aerospace Medicine